| Dataset | ranked_basal_vs_classical |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | CELL CYCLE CHECKPOINTS%REACTOME%R-HSA-69620.5 |
| Enrichment Score (ES) | 0.5710772 |
| Normalized Enrichment Score (NES) | 2.0422742 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.002552139 |
| FWER p-Value | 0.029 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | PSMD2 | 66 | 11.354 | 0.0327 | Yes |
| 2 | MCM4 | 190 | 7.888 | 0.0511 | Yes |
| 3 | UBE2V2 | 344 | 5.862 | 0.0613 | Yes |
| 4 | RFC2 | 370 | 5.705 | 0.0782 | Yes |
| 5 | YWHAQ | 417 | 5.392 | 0.0929 | Yes |
| 6 | CENPH | 426 | 5.332 | 0.1096 | Yes |
| 7 | CHEK1 | 439 | 5.250 | 0.1257 | Yes |
| 8 | MCM2 | 472 | 5.033 | 0.1401 | Yes |
| 9 | RFC4 | 498 | 4.873 | 0.1543 | Yes |
| 10 | MCM7 | 524 | 4.709 | 0.1680 | Yes |
| 11 | NUP107 | 525 | 4.698 | 0.1831 | Yes |
| 12 | CSNK1E | 536 | 4.642 | 0.1974 | Yes |
| 13 | KIF18A | 542 | 4.617 | 0.2119 | Yes |
| 14 | MAPK11 | 673 | 4.052 | 0.2176 | Yes |
| 15 | MCM6 | 700 | 3.947 | 0.2288 | Yes |
| 16 | YWHAG | 753 | 3.814 | 0.2381 | Yes |
| 17 | NEK11 | 875 | 3.477 | 0.2425 | Yes |
| 18 | CDK2 | 976 | 3.265 | 0.2473 | Yes |
| 19 | CENPN | 986 | 3.246 | 0.2572 | Yes |
| 20 | BIRC5 | 1042 | 3.144 | 0.2642 | Yes |
| 21 | SPC24 | 1060 | 3.106 | 0.2732 | Yes |
| 22 | ZNF385A | 1075 | 3.076 | 0.2823 | Yes |
| 23 | CCNB1 | 1076 | 3.072 | 0.2921 | Yes |
| 24 | PSMD14 | 1090 | 3.045 | 0.3012 | Yes |
| 25 | CDC20 | 1109 | 3.009 | 0.3098 | Yes |
| 26 | CDC27 | 1267 | 2.758 | 0.3098 | Yes |
| 27 | BUB1 | 1316 | 2.690 | 0.3158 | Yes |
| 28 | MCM10 | 1356 | 2.623 | 0.3220 | Yes |
| 29 | CDC23 | 1366 | 2.608 | 0.3299 | Yes |
| 30 | TOPBP1 | 1367 | 2.607 | 0.3382 | Yes |
| 31 | KIF2C | 1403 | 2.545 | 0.3444 | Yes |
| 32 | UBE2C | 1408 | 2.534 | 0.3523 | Yes |
| 33 | PHF20 | 1410 | 2.534 | 0.3604 | Yes |
| 34 | CCNB2 | 1456 | 2.462 | 0.3658 | Yes |
| 35 | CENPA | 1468 | 2.442 | 0.3730 | Yes |
| 36 | UBE2E1 | 1492 | 2.414 | 0.3794 | Yes |
| 37 | DYNC1I2 | 1502 | 2.386 | 0.3866 | Yes |
| 38 | CDC6 | 1515 | 2.362 | 0.3935 | Yes |
| 39 | TP53BP1 | 1621 | 2.242 | 0.3948 | Yes |
| 40 | PLK1 | 1658 | 2.202 | 0.3998 | Yes |
| 41 | DYNC1H1 | 1707 | 2.144 | 0.4040 | Yes |
| 42 | CENPO | 1782 | 2.078 | 0.4065 | Yes |
| 43 | PSMD7 | 1890 | 1.986 | 0.4068 | Yes |
| 44 | CDC45 | 1918 | 1.960 | 0.4116 | Yes |
| 45 | MCM5 | 1940 | 1.939 | 0.4166 | Yes |
| 46 | CLASP1 | 1941 | 1.938 | 0.4229 | Yes |
| 47 | PSMA7 | 1948 | 1.930 | 0.4287 | Yes |
| 48 | XPO1 | 1968 | 1.912 | 0.4338 | Yes |
| 49 | CKAP5 | 1981 | 1.899 | 0.4392 | Yes |
| 50 | PSMB2 | 1988 | 1.891 | 0.4449 | Yes |
| 51 | UBE2S | 2058 | 1.832 | 0.4469 | Yes |
| 52 | DSN1 | 2085 | 1.810 | 0.4513 | Yes |
| 53 | CCNA2 | 2090 | 1.806 | 0.4568 | Yes |
| 54 | CSNK1A1 | 2126 | 1.780 | 0.4606 | Yes |
| 55 | GSK3B | 2216 | 1.715 | 0.4611 | Yes |
| 56 | PSMA1 | 2236 | 1.704 | 0.4655 | Yes |
| 57 | PSMD11 | 2302 | 1.658 | 0.4671 | Yes |
| 58 | NUP160 | 2372 | 1.615 | 0.4684 | Yes |
| 59 | PSMD12 | 2441 | 1.574 | 0.4697 | Yes |
| 60 | PSMC3 | 2448 | 1.571 | 0.4744 | Yes |
| 61 | MAD2L1 | 2453 | 1.567 | 0.4792 | Yes |
| 62 | SKA1 | 2468 | 1.560 | 0.4834 | Yes |
| 63 | CLSPN | 2472 | 1.557 | 0.4882 | Yes |
| 64 | UBC | 2489 | 1.548 | 0.4923 | Yes |
| 65 | ZW10 | 2514 | 1.537 | 0.4959 | Yes |
| 66 | CLIP1 | 2532 | 1.523 | 0.4998 | Yes |
| 67 | PKMYT1 | 2552 | 1.513 | 0.5036 | Yes |
| 68 | DYNC1LI1 | 2570 | 1.503 | 0.5074 | Yes |
| 69 | ERCC6L | 2584 | 1.493 | 0.5115 | Yes |
| 70 | KNTC1 | 2598 | 1.485 | 0.5155 | Yes |
| 71 | CENPE | 2603 | 1.482 | 0.5201 | Yes |
| 72 | CENPF | 2616 | 1.475 | 0.5241 | Yes |
| 73 | INCENP | 2650 | 1.455 | 0.5269 | Yes |
| 74 | RCC2 | 2696 | 1.434 | 0.5290 | Yes |
| 75 | CCNE2 | 2783 | 1.388 | 0.5286 | Yes |
| 76 | RBX1 | 2795 | 1.383 | 0.5324 | Yes |
| 77 | CCNE1 | 2832 | 1.366 | 0.5348 | Yes |
| 78 | CDKN2A | 2835 | 1.364 | 0.5391 | Yes |
| 79 | NUP85 | 2838 | 1.361 | 0.5433 | Yes |
| 80 | BUB1B | 2943 | 1.306 | 0.5416 | Yes |
| 81 | CENPP | 2953 | 1.303 | 0.5453 | Yes |
| 82 | CCNA1 | 2965 | 1.298 | 0.5489 | Yes |
| 83 | CENPK | 3003 | 1.277 | 0.5509 | Yes |
| 84 | PPP2R5C | 3125 | 1.218 | 0.5480 | Yes |
| 85 | MAPRE1 | 3143 | 1.212 | 0.5509 | Yes |
| 86 | CENPQ | 3146 | 1.209 | 0.5547 | Yes |
| 87 | YWHAZ | 3197 | 1.186 | 0.5557 | Yes |
| 88 | NDE1 | 3301 | 1.138 | 0.5535 | Yes |
| 89 | PSMB5 | 3376 | 1.113 | 0.5530 | Yes |
| 90 | SKA2 | 3411 | 1.100 | 0.5546 | Yes |
| 91 | NBN | 3416 | 1.098 | 0.5579 | Yes |
| 92 | PSMA6 | 3417 | 1.098 | 0.5614 | Yes |
| 93 | RFC3 | 3428 | 1.090 | 0.5643 | Yes |
| 94 | RFC5 | 3491 | 1.065 | 0.5643 | Yes |
| 95 | CDK1 | 3492 | 1.065 | 0.5677 | Yes |
| 96 | ZWILCH | 3521 | 1.057 | 0.5695 | Yes |
| 97 | PPP2R5E | 3600 | 1.022 | 0.5684 | Yes |
| 98 | RBBP8 | 3693 | 0.983 | 0.5664 | Yes |
| 99 | KIF2A | 3739 | 0.966 | 0.5669 | Yes |
| 100 | CDKN1B | 3795 | 0.939 | 0.5669 | Yes |
| 101 | BRCA1 | 3849 | 0.917 | 0.5668 | Yes |
| 102 | PSMB7 | 3974 | 0.872 | 0.5627 | Yes |
| 103 | ATRIP | 3985 | 0.868 | 0.5649 | Yes |
| 104 | YWHAB | 3999 | 0.864 | 0.5669 | Yes |
| 105 | GTSE1 | 4023 | 0.859 | 0.5684 | Yes |
| 106 | ANAPC10 | 4025 | 0.859 | 0.5711 | Yes |
| 107 | RPA3 | 4178 | 0.802 | 0.5651 | No |
| 108 | CENPI | 4225 | 0.786 | 0.5650 | No |
| 109 | NDC80 | 4337 | 0.753 | 0.5612 | No |
| 110 | RPA2 | 4372 | 0.742 | 0.5617 | No |
| 111 | MDC1 | 4407 | 0.731 | 0.5621 | No |
| 112 | MCM8 | 4527 | 0.691 | 0.5577 | No |
| 113 | RANGAP1 | 4584 | 0.674 | 0.5567 | No |
| 114 | PLK3 | 4814 | 0.615 | 0.5458 | No |
| 115 | ANAPC11 | 4842 | 0.609 | 0.5462 | No |
| 116 | RPA1 | 4850 | 0.606 | 0.5478 | No |
| 117 | AURKB | 4851 | 0.605 | 0.5497 | No |
| 118 | SPC25 | 4876 | 0.598 | 0.5503 | No |
| 119 | NDEL1 | 4983 | 0.578 | 0.5462 | No |
| 120 | WEE1 | 5069 | 0.558 | 0.5432 | No |
| 121 | UBE2D1 | 5077 | 0.555 | 0.5446 | No |
| 122 | PSMA2 | 5298 | 0.503 | 0.5338 | No |
| 123 | PSMC1 | 5307 | 0.501 | 0.5350 | No |
| 124 | RAD1 | 5358 | 0.492 | 0.5338 | No |
| 125 | NUF2 | 5382 | 0.487 | 0.5340 | No |
| 126 | SEC13 | 5389 | 0.485 | 0.5352 | No |
| 127 | BRIP1 | 5425 | 0.476 | 0.5348 | No |
| 128 | CDC25C | 5478 | 0.464 | 0.5334 | No |
| 129 | EXO1 | 5484 | 0.463 | 0.5346 | No |
| 130 | CENPL | 5587 | 0.440 | 0.5303 | No |
| 131 | PPP2R5B | 5669 | 0.419 | 0.5270 | No |
| 132 | YWHAE | 5731 | 0.407 | 0.5249 | No |
| 133 | PSMD8 | 5752 | 0.402 | 0.5251 | No |
| 134 | CDC7 | 5779 | 0.398 | 0.5249 | No |
| 135 | CDC25A | 5867 | 0.383 | 0.5212 | No |
| 136 | PSMC2 | 5885 | 0.380 | 0.5215 | No |
| 137 | MAD1L1 | 6022 | 0.354 | 0.5150 | No |
| 138 | RNF168 | 6136 | 0.334 | 0.5097 | No |
| 139 | ITGB3BP | 6180 | 0.325 | 0.5084 | No |
| 140 | TOP3A | 6200 | 0.323 | 0.5083 | No |
| 141 | MDM2 | 6219 | 0.320 | 0.5083 | No |
| 142 | BLM | 6233 | 0.318 | 0.5086 | No |
| 143 | ATR | 6328 | 0.304 | 0.5043 | No |
| 144 | TP53 | 6367 | 0.297 | 0.5031 | No |
| 145 | RAD17 | 6393 | 0.293 | 0.5027 | No |
| 146 | ANAPC1 | 6407 | 0.289 | 0.5029 | No |
| 147 | DBF4 | 6542 | 0.271 | 0.4962 | No |
| 148 | DYNLL2 | 6684 | 0.252 | 0.4891 | No |
| 149 | PSMD13 | 6734 | 0.246 | 0.4871 | No |
| 150 | ADRM1 | 6737 | 0.245 | 0.4878 | No |
| 151 | PSMA4 | 6797 | 0.237 | 0.4853 | No |
| 152 | CUL1 | 6814 | 0.236 | 0.4851 | No |
| 153 | PSMC6 | 6967 | 0.213 | 0.4773 | No |
| 154 | PPP2R5D | 7056 | 0.200 | 0.4730 | No |
| 155 | PAFAH1B1 | 7294 | 0.170 | 0.4602 | No |
| 156 | PPP2CB | 7314 | 0.168 | 0.4597 | No |
| 157 | PSMD3 | 7435 | 0.151 | 0.4534 | No |
| 158 | UIMC1 | 7486 | 0.144 | 0.4511 | No |
| 159 | PPP2R1A | 7605 | 0.130 | 0.4448 | No |
| 160 | ATM | 7694 | 0.120 | 0.4403 | No |
| 161 | CHEK2 | 7698 | 0.120 | 0.4405 | No |
| 162 | BARD1 | 7739 | 0.116 | 0.4386 | No |
| 163 | TAOK1 | 7771 | 0.112 | 0.4372 | No |
| 164 | PPP2CA | 8037 | 0.087 | 0.4226 | No |
| 165 | RNF8 | 8046 | 0.086 | 0.4225 | No |
| 166 | PSMA3 | 8053 | 0.086 | 0.4224 | No |
| 167 | DNA2 | 8101 | 0.081 | 0.4200 | No |
| 168 | ZWINT | 8121 | 0.079 | 0.4192 | No |
| 169 | RPS27A | 8359 | 0.056 | 0.4061 | No |
| 170 | DYNLL1 | 8464 | 0.047 | 0.4004 | No |
| 171 | PSMC4 | 8478 | 0.046 | 0.3998 | No |
| 172 | NUP37 | 8486 | 0.046 | 0.3996 | No |
| 173 | PSMB6 | 8503 | 0.044 | 0.3988 | No |
| 174 | BUB3 | 8514 | 0.043 | 0.3984 | No |
| 175 | PCBP4 | 8712 | 0.021 | 0.3874 | No |
| 176 | HERC2 | 8728 | 0.020 | 0.3866 | No |
| 177 | HUS1 | 8737 | 0.019 | 0.3862 | No |
| 178 | PSMC5 | 8836 | 0.008 | 0.3807 | No |
| 179 | SKP1 | 8856 | 0.006 | 0.3797 | No |
| 180 | RMI1 | 9002 | -0.008 | 0.3716 | No |
| 181 | CDC26 | 9028 | -0.010 | 0.3702 | No |
| 182 | CDCA8 | 9118 | -0.019 | 0.3652 | No |
| 183 | KAT5 | 9774 | -0.086 | 0.3287 | No |
| 184 | MAPK14 | 9907 | -0.102 | 0.3216 | No |
| 185 | NUP133 | 9957 | -0.107 | 0.3192 | No |
| 186 | RAD50 | 10117 | -0.127 | 0.3107 | No |
| 187 | WRN | 10261 | -0.145 | 0.3031 | No |
| 188 | CENPT | 10317 | -0.152 | 0.3005 | No |
| 189 | PSMD6 | 10345 | -0.156 | 0.2995 | No |
| 190 | PSMB3 | 10388 | -0.162 | 0.2977 | No |
| 191 | CLASP2 | 10555 | -0.184 | 0.2889 | No |
| 192 | PSMD1 | 10589 | -0.188 | 0.2877 | No |
| 193 | PSMB4 | 10737 | -0.209 | 0.2801 | No |
| 194 | PSMA5 | 11175 | -0.271 | 0.2564 | No |
| 195 | CDKN1A | 11370 | -0.303 | 0.2465 | No |
| 196 | ANAPC5 | 11442 | -0.314 | 0.2435 | No |
| 197 | ANAPC16 | 11587 | -0.338 | 0.2365 | No |
| 198 | FBXW11 | 11628 | -0.344 | 0.2354 | No |
| 199 | CDC16 | 11680 | -0.355 | 0.2336 | No |
| 200 | SFN | 11683 | -0.355 | 0.2347 | No |
| 201 | PSMB1 | 11762 | -0.373 | 0.2315 | No |
| 202 | NUDC | 11871 | -0.393 | 0.2267 | No |
| 203 | UBE2N | 12069 | -0.432 | 0.2170 | No |
| 204 | DYNC1LI2 | 12082 | -0.434 | 0.2177 | No |
| 205 | PPP2R1B | 12139 | -0.445 | 0.2160 | No |
| 206 | RANBP2 | 12494 | -0.522 | 0.1978 | No |
| 207 | RPS27 | 12632 | -0.554 | 0.1918 | No |
| 208 | BTRC | 12676 | -0.565 | 0.1912 | No |
| 209 | ANAPC2 | 12794 | -0.588 | 0.1866 | No |
| 210 | UBA52 | 12867 | -0.609 | 0.1845 | No |
| 211 | NUP43 | 13038 | -0.649 | 0.1770 | No |
| 212 | CENPM | 13305 | -0.717 | 0.1643 | No |
| 213 | PPP1CC | 13356 | -0.729 | 0.1639 | No |
| 214 | BRCC3 | 13492 | -0.763 | 0.1587 | No |
| 215 | PMF1 | 13555 | -0.781 | 0.1578 | No |
| 216 | NSL1 | 13680 | -0.819 | 0.1534 | No |
| 217 | MDM4 | 13865 | -0.885 | 0.1459 | No |
| 218 | B9D2 | 14160 | -0.983 | 0.1326 | No |
| 219 | ANAPC7 | 14332 | -1.052 | 0.1263 | No |
| 220 | MCM3 | 14404 | -1.086 | 0.1258 | No |
| 221 | RAD9A | 14581 | -1.164 | 0.1197 | No |
| 222 | YWHAH | 14611 | -1.172 | 0.1218 | No |
| 223 | AHCTF1 | 14647 | -1.187 | 0.1236 | No |
| 224 | MIS12 | 15035 | -1.390 | 0.1063 | No |
| 225 | ANAPC4 | 15110 | -1.436 | 0.1068 | No |
| 226 | UBB | 15321 | -1.549 | 0.1000 | No |
| 227 | RAD9B | 15689 | -1.811 | 0.0852 | No |
| 228 | PIAS4 | 15857 | -1.944 | 0.0820 | No |
| 229 | DYNC1I1 | 16047 | -2.125 | 0.0782 | No |
| 230 | PPP2R5A | 17902 | -10.317 | 0.0071 | No |
